Patent · US Expired

1,3-disubstituted pyrrolidines

US5274097A · kind A · utility

16Cited by

5References

4Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Rudolf Schohe · Wuppertal, DE
Peter-Rudolf Seidel · Cologne, DE
Jorg Traber · Lohmar, DE
Thomas Glaser · Overath, DE

Key dates

Filing date	Apr 9, 1991
Grant date	Dec 28, 1993
Priority date	—
Expiry date	Apr 9, 2011

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/06
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Novel 1,3-disubstituted pyrrolidines active on the central nervous system of the formula ##STR1## wherein A--denotes phenyl or hetaryl, which is optionally fused with aromatic, saturated or unsaturated cyclic or heterocyclic hydrocarbons, where this radical can optionally be substituted, PA1 X--denotes --O--CH.sub.2 --, --CH.sub.2 --O-- or --O--, PA1 n--denotes a number from 1 to 19, and PA1 B--denotes cyano or a group of the formula --COOR.sup.1, --CONR.sup.2 R.sup.3, --SO.sub.2 NR.sup.2 R.sup.3, --SO.sub.m R.sup.4, --NR.sup.5 R.sup.6, or --C.tbd.C--CH.sub.2 --NR.sup.5 R.sup.6, and salts thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.