Octalactone-containing composition, fermentation process for producing same and organoleptic uses thereof
US5274128A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 22, 1992 |
| Grant date | Dec 28, 1993 |
| Priority date | — |
| Expiry date | May 22, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/911
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Described is a process for the preparation of compositions of matter containing octalactones defined according to the structure: ##STR1## which includes the stereoisomers having the structures: ##STR2## by means of the sequential steps of (i) fermentation of caprylic acid or the ethyl ester of caprylic acid defined according to the generic structure: ##STR3## wherein R is hydrogen or ethyl using a microorganism selected from the group consisting of: PA1 Mortierella ramanniana var. ramanniana--CBS 112.08 PA1 Mortierella ramanniana var. ramanniana--CBS 478.63 PA1 Choanephora cucurbitarum--NRRL 2744 PA1 Mortierella isabellina--IFO 8183 PA1 Mortierella isabellina--IFO 8309 PA1 Mortierella nana--IFO 8794 PA1 Mortierella isabellina--IFO 7824 PA1 Mortierella vinacea--IFO 6738 whereby a gamma hydroxy octanoic acid defined according to the structure: ##STR4## is formed; and (ii) lactonization of the resulting gamma hydroxy octanoic acid by means of simultaneous acidification and heating according to the reaction sequence: ##STR5##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.