Preparation of N-substituted lactams

US5276165A · kind A · utility

Assignee

• BASF SE

Inventors

• Hans-Juergen Weyer · Mannheim, DE
• Rolf Fischer · Heidelberg, DE

Key dates

• Filing date: Nov 25, 1992
• Grant date: Jan 4, 1994
• Expiry date: Nov 25, 2012

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D207/267
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the preparation of N-substituted lactams of the formula I ##STR1## where Z is C.sub.2 - to C.sub.10 -alkylene, C.sub.7 - to C.sub.12 -aralkylene, phenylene or naphthylene, and PA1 R.sup.1 is C.sub.1 - to C.sub.20 -alkyl, C.sub.6 - to C.sub.10 -aryl or C.sub.7 - to C.sub.12 -aralkyl, by hydrogenating a compound of the formula II ##STR2## where W is C.sub.2 - to C.sub.10 -alkylene, C.sub.2 - to C.sub.10 -alkenylene, C.sub.7 - to C.sub.12 -aralkylene, phenylene or naphthylene, and PA1 X and Y together form an oxa or imido bridge of the formula ##STR3## or alternatively are identical or different and are hydroxyl, C.sub.1 - to C.sub.20 -alkoxy, C.sub.6 - to C.sub.10 -aryloxy or C.sub.7 - to C.sub.12 -aralkoxy, and, if X and Y are different, Y, in addition to the abovementioned meanings, may also be hydrogen, at superatmospheric pressure and at elevated temperature in the presence of a catalyst and in the presence of an amine, which comprises using a secondary and/or tertiary amine of the formula III EQU NH.sub.n R.sub.3-n .sup.1 where R.sup.1 is as defined above and n is 0 or 1, or a mixture of a secondary and/or teritary amine of this type with a primary amine of the for…