Soluble alkyl[5-[amino (phenyl)methyl]-1H-benzimidazol-2-yl] carbamate anthelmintics
US5278181A · kind A · utility
3Cited by
3References
6Claims
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Assignee
Inventors
Key dates
| Filing date | May 12, 1992 |
| Grant date | Jan 11, 1994 |
| Priority date | — |
| Expiry date | May 12, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D235/32
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Soluble alkyl [5-(amino (phenyl)methyl)-2H-benzimidazol-2-yl]carbamates, their enantiomorphic forms, and acid addition salts thereof are well absorbed and possess curative anthelmintic activity, especially against filarial worms, when administered orally or parenterally. Pharmaceutical compositions containing the compounds and methods of employing the compounds in methods of treating helminth infections in mammals are also disclosed, together with methods of synthesis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.