Binding protein for CEA and uses thereof
US5278290A · kind A · utility
0Cited by
8References
27Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | May 31, 1991 |
| Grant date | Jan 11, 1994 |
| Priority date | — |
| Expiry date | May 31, 2011 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/828
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is a protein that specifically binds carcinoembryonic actigen (CEA) in the presence of divalent cation in vitro. This protein has a molecular weight of about 21 kD as determined by SDS-polyacrylamide gel electrophoresis, is glycosylated, and includes the amino acid sequence set forth in the Sequence Listing as SEQ ID NO: 2. Also disclosed are antibodies that recognize the CEA binding protein, methods of detecting carcinoma, methods of treating carcinoma, and a kit for screening a patient for carcinoma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.