Patent · US Expired

Process for the preparation of 1,3-dioxane derivatives useful in the preparation of HMG-COA reductase inhibitors

US5278313A · kind A · utility

29Cited by
12References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 27, 1992
Grant dateJan 11, 1994
Priority date
Expiry dateMar 27, 2012

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C69/716
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A novel, overall process for the preparation of a compound of the formula I: ##STR1## where R.sup.1 and R.sup.2 are each independently hydrogen, an alkyl group, a cycloalkyl group, an aryl group or, taken together with the carbon atom to which they are attached, form a cycloalkyl group; and PA1 R.sup.3 is hydrogen, an alkyl group, or an aryl group, or salts thereof, useful as intermediates in the preparation of HMG-CoA reductase inhibitors; novel methods within the overall process; and novel intermediates produced by those methods.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.