Process to make magnetically responsive fluorescent polymer particles
US5283079A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 14, 1989 |
| Grant date | Feb 1, 1994 |
| Priority date | — |
| Expiry date | Dec 14, 2009 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2446/86
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention provides a novel process of producing magnetically responsive fluorescent polymer particles comprising polymeric core particles coated evenly with a layer of polymer containing magnetically responsive metal oxide. A wide variety of polymeric particles with sizes ranging from 1 to 100 microns can be used a core particles and transformed into magnetically responsive polymer particles. The surface of these magnetically responsive polymer particles can be coated further with another layer of functionalized polymer. These magnetically responsive fluorescent polymer particles can be used for passive or covalent coupling of biological material such as antigens, antibodies, enzymes or DNA/RNA hybridization and used as solid phase for various types of immunoassays, DNA/RNA hybridization probes assays, affinity purification, cell separation and other medical, diagnostic, and industrial applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.