Cholesterol-lowering agents
US5283256A · kind A · utility
19Cited by
8References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 22, 1992 |
| Grant date | Feb 1, 1994 |
| Priority date | — |
| Expiry date | Jul 22, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01N43/90
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to compounds of structural formula (I): ##STR1## which are squalene synthase inhibitors and thus useful as cholesterol lowering agents and antifungal agents. These compounds are also inhibitors of farnesyl protein transferase and farnesylation of the oncogene protein Ras and thus useful in treating cancer. This invention also relates to a process for obtaining compounds of structural formula (I).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.