Process and device for the determination of local dye concentrations and of scattering parameters in animal and human tissues
US5284137A · kind A · utility
Inventors
Key dates
| Filing date | Dec 2, 1991 |
| Grant date | Feb 8, 1994 |
| Priority date | — |
| Expiry date | Dec 2, 2011 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/314
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates specifically to a process for the determination of local dye concentrations in animal and human tissues. Light from two different wavelength regions (I, II), one of which (I) has a window for hemoglobin, is irradiated into a subregion of the tissue and the diffuse reflectance (MIO, MIIO) determined. Then, in another step, by means of the diffuse reflectance in the first wavelength region and at least one tissue-type-specific standard basic diffuse reflectance curve obtained in advance for both wavelength regions a tissue-person-specific standard basic diffuse reflectance curve (SIIO) for the second wavelength region (II) is determined, and by means of the determined tissue-person-specific standard basic diffusereflectance curve (SIIO) and the measured diffuse reflectance (MIIO) in the second wavelength region (II) a value for the hemoglobin concentration (KHb1) is obtained.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.