Nucleic acid probes to Coccidioides immitis
US5284747A · kind A · utility
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2References
4Claims
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Key dates
| Filing date | Dec 18, 1991 |
| Grant date | Feb 8, 1994 |
| Priority date | — |
| Expiry date | Dec 18, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6895
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A nucleotide polymer probe having the nucleotide sequence of SEQ ID NO. 1 or SEQ ID NO. 6 able to hybridize at 60.degree. C. in 0.1M lithium succinate buffer containing 10% lithium lauryl sulfate to rRNA or rDNA from Coccidioides immitis and not to rRNA or rDNA from Auxarthron thaxteri, Blastomyces dermatitidis, Geotrichum candidum, Gymnoascus dugwayensis, Histoplasma capsulatum, and Malbranchea albolutea. A method to distinguish Coccidioides immitis from Auxarthron thaxteri, Blastomyces dermatitidis, Geotrichum candidum, Gymnoascus dugwayensis, Histoplasma capsulatum, and Malbranchea albolutea using said probe is also disclosed.
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