Biological production of acetal or ketal substituted benzene compounds
US5284759A · kind A · utility
3Cited by
1References
9Claims
0Family size
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Key dates
| Filing date | Aug 17, 1992 |
| Grant date | Feb 8, 1994 |
| Priority date | — |
| Expiry date | Aug 17, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P17/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Meta-hydroxyphenylacetylenes are produced from phenyl-substituted ketal or acetal precursors. Using biotransformation processes, these precursors serve as substrates that are converted to cis-dihydrodiol intermediates. The cis-dihydrodiols can be converted chemically to the corresponding meta-substituted compounds, e.g., meta-substituted phenols, and then to m-hydroxyphenylacetylene, which is an intermediate needed to produce acetylene-terminated resins. The biotransformation step employs arene-2,3-dioxygenase in intra- or extra- cellular form.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.