Process for preparing a single enantiomer of a lactam using lactamase
US5284769A · kind A · utility
15Cited by
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20Claims
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Key dates
| Filing date | May 20, 1993 |
| Grant date | Feb 8, 1994 |
| Priority date | — |
| Expiry date | May 20, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P41/006
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Lactams of 1-amino-3-carboxylic acid cyclic compounds are produced in enantiomeric form, together with an enantiomer of the corresponding ring-opened amino-acid or ester, by reaction of the racemic lactam with a novel lactamase. The products are useful in the synthesis of chiral carbocyclic nucleotides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.