0-hydroxyethyl and acyloxyethyl derivatives of [ser].sup.8 cyclosporins
US5284826A · kind A · utility
76Cited by
1References
12Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 27, 1992 |
| Grant date | Feb 8, 1994 |
| Priority date | — |
| Expiry date | Aug 27, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Hydroxy-substituted [(D)Ser].sup.8 -Ciclosporin derivatives, particularly [O-(2-hydroxyethyl)(D)Ser].sup.8 -Ciclosporin, have advantageous pharmacological properties and are useful as immunosuppressants, for example in the treatment of transplant rejection and autoimmune diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.