Stabilized controlled release formulations having acrylic polymer coating
US5286493A · kind A · utility
430Cited by
5References
35Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 27, 1992 |
| Grant date | Feb 15, 1994 |
| Priority date | — |
| Expiry date | Jan 27, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/5078
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A stabilized solid controlled release dosage form having a coating derived from an aqueous dispersion of an acrylic polymer is obtained by overcoating a substrate including a therapeutically active with an aqueous dispersion of the plasticized acrylic polymer and then curing the coated substrate at a temperature above the glass transition temperature of the plasticized acrylic polymer, until the coated dosage form attains a stabilized dissolution profile substantially unaffected by exposure to storage conditions of elevated temperature and/or elevated relative humidity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.