Patent · US Expired

Method for detecting the .gamma.,.delta. T cell receptor

US5286653A · kind A · utility

1Cited by

5References

60Claims

0Family size

Assignees

T Cell Diagnostics, Inc. · US
DANA-FARBER CANCER INSTITUTE, INC. · US
President and Fellows of Harvard College · US

Inventors

Michael B. Brenner · Ashland, US
Jack L. Strominger · Lexington, US
Jonathan Seidman · Milton, US
Stephen H. Ip · Sudbury, US
Michael S. Krangel · Newton, US

Key dates

Filing date	Jul 3, 1986
Grant date	Feb 15, 1994
Priority date	—
Expiry date	Jul 3, 2006

Classification

Technology area (CPC G)Physics
CPC primaryG01N33/56972
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention provides purified polypeptides which comprise at least a portion of a .delta.T cell receptor polypeptide, a .gamma.T cell receptor polypeptide or a .gamma.,.delta. T cell receptor complex. Substances capable of forming complexes with these polypeptides are also provided. Additionally, methods for detecting T cells which have within them or on their surfaces a polypeptide of the present invention are provided. Moreover, methods for diagnosing immune system abnormalities are provided which comprise measuring in a sample from a subject the number of T cells which have within them or on their surfaces a polypeptide of the present invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.