Inhibitor of the proliferation of endothelial cells

US5286716A · kind A · utility

Assignee

• Max-Planck-Gesellschaft zur Föderung der Wissenschaften e.V. · US

Inventors

• Werner Risau · Gräfelfing, DE
• Hannes Drexler · Hersbruck, DE

Key dates

• Filing date: Aug 25, 1992
• Grant date: Feb 15, 1994
• Expiry date: Aug 25, 2012

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K14/4703
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Protein which acts as an inhibitor of the proliferation of endothelial ce which is obtainable from baby hamster kidney cells (ATCC CCL 10) and has a molecular weight between 60 and 100 kD in gel filtration under native conditions and is thermally stable at 60.degree. C., as well as a process for its isolation and its use in the treatment of diseases.