Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
US5286726A · kind A · utility
11Cited by
17References
6Claims
0Family size
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Inventors
Key dates
| Filing date | Apr 12, 1990 |
| Grant date | Feb 15, 1994 |
| Priority date | — |
| Expiry date | Apr 12, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to certain conjugates of folates and antifolates with difluoroglutamic acid which are useful in the treatment of patients suffering from certain neoplastic diseases including leukemia, melanomas, carcinomas, sarcomas and mixed neoplasias.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.