Patent · US Expired

Sterodial liposomes

US5288499A · kind A · utility

20Cited by
17References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 12, 1991
Grant dateFeb 22, 1994
Priority date
Expiry dateSep 12, 2011

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T428/2984
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Methods and compositions are described for the preparation of bioactive agents entrapped in lipid vesicles the bilayers of which comprise a salt form of an organic acid derivative of a sterol, such as the tris-salt form of a sterol hemisuccinate, and to compositions comprising a mixture of tris(hydroxymethyl)aminomethane salt of cholesteryl hemisuccinate with either an antifungal compound or a peptide. These compositions have various applications in vivo.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.