Method for the detection of malignant diseases
US5288614A · kind A · utility
16Cited by
2References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 23, 1991 |
| Grant date | Feb 22, 1994 |
| Priority date | — |
| Expiry date | Jul 23, 2011 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/828
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
In order to aid in the detection of malignant diseases the sample of a body fluid is incubated with at least two receptors R.sub.1 and R.sub.2 in which a signal change is produced by binding of at least the receptors R.sub.1 and R.sub.2 to the substance to be detected in the sample solution and in which one of the two receptors contains a monoclonal antibody which binds to the amino acid sequence 311 to 335 of cytokeratin 19 and the other receptor contains a monoclonal antibody which binds to the amino acid sequence 346 to 359 of cytokeratin 19 and the signal change in the sample caused by the binding is determined.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.