Substituted .beta.-diketones

US5288750A · kind A · utility

Assignee

• Orion-Yhtyma OY · FI

Inventors

• Pentti Pohto · Helsinki, FI
• Paivi A. Aho · Helsinki, FI
• Reijo Backstrom · Helsinki, FI
• Erkki J. Honkanen · Vantaa, FI
• Inge-Britt Y. Linden · Espoo, FI
• Erkki A. O. Nissinen · Espoo, FI

Key dates

• Filing date: Jan 31, 1991
• Grant date: Feb 22, 1994
• Expiry date: Jan 31, 2011

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P1/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

##STR1## wherein R.sub.1 and R.sub.2 are each independently hydrogen, alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, hydroxy, aryl or heteroaryl or amino, the alkyl, aryl, heteroaryl or amino group being optionally substituted; R.sub.3 is hydrogen, optionally substituted alkyl of 1 to 6 carbon atoms or optionally substituted aryl or heteroaryl and salts, ethers and esters thereof are useful as cytoprotective agents, especially as antitulcerogenic or gastroprotective agents.