New urea derivatives, their preparation and their application in therapy
US5288758A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 22, 1992 |
| Grant date | Feb 22, 1994 |
| Priority date | — |
| Expiry date | Jul 22, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C335/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
New urea derivatives corresponding to the general formula 1 ##STR1## in which: R.sup.1 represents a C.sub.1 -C.sub.4 alkyl group; PA0 R.sup.2 represents: PA1 a C.sub.5 -C.sub.7 cycloalkyl group PA1 a cycloalkylmethyl group in which the cycloalkyl radical contains from 5 to 7 carbon atoms PA1 a benzyl group PA1 a benzyl group in which the aromatic ring bears a C.sub.1 -C.sub.4 alkyl group, a C.sub.1 -C.sub.4 alkoxy group, a halogen atom or a nitro group; PA1 A represents an oxygen atom or a methylene radical; PA1 n represents 1 or 2; PA0 X represents an oxygen or sulfur atom; PA0 B represents a direct bond, a methylene radical or a carbonyl radical; as well as the therapeutically acceptable salts of these molecules. The invention also relates to the application of the compounds of general formula 1 in therapy, and to the preparation processes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.