3,5-di-t-butyl-4-hydroxylphenylmethylhydroxylamines and their derivatives, pharmaceutical compositions, and methods of use therefor
US5288896A · kind A · utility
8Cited by
0References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 15, 1992 |
| Grant date | Feb 22, 1994 |
| Priority date | — |
| Expiry date | Jan 15, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C335/40
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is a novel compound which is a 3,5-di-t-butyl-4-hydroxyphenylmethylhydroxylamine or derivative thereof and a pharmaceutically acceptable acid addition or base salt thereof, pharmaceutical composition and methods of use therefor. The invention compounds are now found to have activity as inhibitors of one or both of cyclooxygenase and 5-lipoxygenase providing treatment of conditions advantageously affected by such inhibition including inflammation, arthritis, pain, fever, and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.