Immunosuppressant agent
US5290772A · kind A · utility
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2Claims
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Assignee
Inventors
Key dates
| Filing date | Jun 16, 1992 |
| Grant date | Mar 1, 1994 |
| Priority date | — |
| Expiry date | Jun 16, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/01
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Described is a process for producing an immunosuppressant, "demethimmunomycin" (L-683,7411) a C-31 demethylated analog of L-683,590 under fermentation conditions utilizing the microorganism, Actinoplanacete sp, (Merck Culture Collection MA 6559) ATCC No. 53771. The macrolide immunosuppressant is useful in preventing human host rejection of foreign organ transplants, e.g. bone marrow and heart transplants.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.