Preparation of hapalindole-related alkaloids from blue-green algae
US5292650A · kind A · utility
2Cited by
2References
10Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Sep 16, 1992 |
| Grant date | Mar 8, 1994 |
| Priority date | — |
| Expiry date | Sep 16, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/946
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
New hapalindole-type alkaloids called A89271 A-F and I are antifungal and antitumor agents. Methods for preparing them and for preparing hapalindoles G and H by culturing the blue-green alga Fischerella ambigua ATCC 55210 are provided. Methods for preparing A89271 factors B and F by culturing the blue-green alga Hapalosiphon hibernicus ATCC 55225 and a biologically pure culture of this alga are also provided. Further provided are methods and compositions for the inhibition of fungal growth and the treatment of susceptible neoplasms.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.