24-Oxa derivatives in the vitamin D series

US5292728A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Gunter Neef · Berlin, DE
• Gerald Kirsch · Berlin, DE
• Andreas Steinmeyer · Berlin, DE
• Katica Schwarz · Berlin, DE
• Matthias Brautigam · Berlin, DE
• R. Thieroff-Ekerdt · Berlin, DE
• Petra Rach · Berlin, DE

Key dates

• Filing date: Dec 4, 1992
• Grant date: Mar 8, 1994
• Expiry date: Dec 4, 2012

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C401/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

New 24-oxa derivatives in the vitamin D series of general formula I are described in which PA1 R.sup.1, R.sup.2 and R.sup.5, independently of one another, mean a hydrogen atom or an acyl group with 1 to 9 carbon atoms, PA1 R.sup.3 means a hydrogen atom or a linear or branched alkyl group with 1 to 4 carbon atoms and PA1 R.sup.4 means a hydrogen atom each or a linear or branched alkyl group each with 1 to 4 carbon atoms. Pharmaceutical preparations which contain these compounds are also disclosed.