Method of screening for antimitotic compounds using the CDC25 tyrosine phosphatase
US5294538A · kind A · utility
15Cited by
0References
4Claims
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Inventor
Key dates
| Filing date | May 5, 1992 |
| Grant date | Mar 15, 1994 |
| Priority date | — |
| Expiry date | May 5, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of identifying compounds or molecules which alter (enhance or inhibit) stimulation of kinase activity of pre-MPF and, thus, alter (enhance or inhibit) activation of MPF and entry into mitosis. The present method thus makes it possible to identify compounds or molecules which can be administered to regulate the cell cycle; such compounds are also the subject of this invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.