Biologically active factor
US5294544A · kind A · utility
3Cited by
6References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 22, 1992 |
| Grant date | Mar 15, 1994 |
| Priority date | — |
| Expiry date | May 22, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/838
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention comprises a factor having the following characteristics: PA1 a) It inhibits granulocyte-macrophage colony and cluster formation; PA1 b) It has a molecular weight of about 8 kDa as determined by SDS-PAGE; PA1 c) It has a weak anionic charge at pH 7.4 as shown by anion exchange chromatography; PA1 d) It has a flattened isoelectric titration curve as shown by anion exchange chromatography; and PA1 d) It is a protein. The invention also comprises methods of making and using the factor and compositions comprising the factor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.