Patent · US Expired

6-heterocyclyl pyrazolo [3,4-d]pyrimidin-4-ones and compositions and method of use thereof

US5294612A · kind A · utility

194Cited by

8References

15Claims

0Family size

Assignee

Sterling Winthrop Inc. · US

Inventors

Edward R. Bacon · East Greenbush, US
Baldev Singh · East Greenbush, US
George Y. Lesher · Rockville Centre, US

Key dates

Filing date	Mar 30, 1992
Grant date	Mar 15, 1994
Priority date	—
Expiry date	Mar 30, 2012

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D487/04
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Novel 6-heterocyclyl-pyrazolo[3,4-d]pyrimidin-4-ones, useful in treating cardiovascular disease, are prepared by reacting a 5-amino-1H-pyrazole-4-carboxamide with heterocyclylcarboxaldehyde or by reacting a 5-amino-1H-pyrazole-4-carbonitrile with a heterocyclylcarboxamidine, followed by diazotization and hydrolysis of the resulting 4-amino-6-heterocyclyl-pyrazolo[3,4-d]pyrimidine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.