Human phospholipase activating protein and methods for diagnosis of rheumatoid arthritis
US5294698A · kind A · utility
Inventors
Key dates
| Filing date | Dec 6, 1990 |
| Grant date | Mar 15, 1994 |
| Priority date | — |
| Expiry date | Dec 6, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/61
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides methods for detecting elevated levels of phospholipase A.sub.2 activating protein in persons suspected of having rheumatiod arthritis to thereby indicate the presence of rheumatoid arthritis in the person comprising the steps of providing a sample of body fluid or tissue from said person; contacting the sample with an antibody specific for phospholipase A.sub.2 activating protein such that the antibody binds with phospholipase A.sub.2 activating protein in the sample; detecting the antibody thereby indicating the presence of phospholipase A.sub.2 activating protein, whereby elevated levels of phospholipase A.sub.2 activating protein in the sample as compared with levels found in persons not having rheumatoid arthritis indicates the presence of rheumatoid arthritis in the person. Kits and reagents for detecting rheumatoid arthritis are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.