Acridine-intercalator based hypoxia selective cytotoxins
US5294715A · kind A · utility
16Cited by
2References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 1, 1991 |
| Grant date | Mar 15, 1994 |
| Priority date | — |
| Expiry date | Feb 1, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Hypoxia selective cytotoxins of the general formula ##STR1## wherein n is from 1 to 5, and NO.sub.2 is in at least one of the 2, 4 or 5-positions of the imidazole. Such compounds have utility as radiosensitizers and chemosensitizers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.