Chemical process for making angiotesin II antagonist compounds
US5294716A · kind A · utility
7Cited by
0References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 17, 1992 |
| Grant date | Mar 15, 1994 |
| Priority date | — |
| Expiry date | Jan 17, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides a novel chemical process for the manufacture of quinoline, pyridine and imidazole derivatives of the formula IV wherein Q, Y.sup.1 and Y.sup.2 have the various meanings defined herein, and their non-toxic salts, which are angiotensin II inhibitors. The process involves the removal of an electron-deficient phenyl group or a pyridyl or pyrimidyl group from a compound of the formula VI as defined herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.