Immunosuppressive macrocyclic compounds
US5296489A · kind A · utility
2Cited by
0References
9Claims
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Assignee
Inventors
Key dates
| Filing date | Sep 11, 1992 |
| Grant date | Mar 22, 1994 |
| Priority date | — |
| Expiry date | Sep 11, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/01
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
There are provided compounds of formula (I), wherein R.sup.1 represents H, OH or alkoxy; R.sup.2 represents H; in addition R.sup.1 and R.sup.2 may together represent a second bond between the carbon atoms to which they are attached; R.sup.3 represents methyl, ethyl, propyl or allyl; R.sup.4 represents H, OH, alkyl, alkoxy, halogen, amino, S-alkyl, NHCHO or NHCO-alkyl; n represents 1 or 2; X represents O, (H, OH), (H, H) or .dbd.NH; and Y represents an optionally substituted cyclohexyl or substituted cyclopentyl group; with various provisos. The compounds are useful, inter alia, as immunosuppressive agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.