Screening method for controlling agranulocytosis
US5300422A · kind A · utility
7Cited by
1References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 4, 1991 |
| Grant date | Apr 5, 1994 |
| Priority date | — |
| Expiry date | Dec 4, 2011 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/815
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A screening method for detecting the vulnerability of patients on clozapine therapy to developing agranulocytosis which comprises establishing the concentration of N-desmethylclozapine in the blood or bone marrow of said patient. In addition, a method of determining patient sensitivity to N-desmethylclozapine is provided which comprises collecting heparinized blood and assaying it for stem cell sensitivity to N-desmethylclozapine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.