Patent · US Expired

Bactericidal and/or bacteriostatic peptides isolated from hemolymph of honeybees

US5300629A · kind A · utility

8Cited by

0References

5Claims

0Family size

Assignee

Plant Genetic Systems N.V. · BE

Inventors

Peter Casteels · Bambrugge, BE
Paul Tempst · New York, US
Frans Jacobs · Scheldewindeke, BE
Mark Vaeck · Zemst, BE

Key dates

Filing date	Nov 14, 1991
Grant date	Apr 5, 1994
Priority date	—
Expiry date	Nov 14, 2011

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S530/858
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

New bactericidal and/or bacteriostatic, thermostable peptides which are isolated from hemolymph of immune honeybees and which are distinct from lysozymes, attacins, cecropins, diptericins and magainins. The peptides feature at least the 10 C-terminal amino acids of the following peptide: PA0 H.sub.2 N-Gly-Asn-Asn-Arg-Pro-X-Tyr-Ile-Pro-Gln-Pro-Arg-Pro-Pro-His-Pro-Arg-Z-OH in which PA0 X is a valyl or isoleucyl residue and PA0 Z is a leucyl or isoleucyl residue.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.