Chelating agents for forming complexes with radioactive isotopes, metal complexes thereof and use thereof in diagnosis and therapy

US5302370A · kind A · utility

Assignee

• Institut fur Diagnosikforschung GmbH · DE

Inventors

• Reinhard Neumeier · Berlin, DE
• Wolfgang Kramp · Berlin, DE
• Helmut Macke · Lörrach, DE

Key dates

• Filing date: Aug 22, 1990
• Grant date: Apr 12, 1994
• Expiry date: Aug 22, 2010

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2123/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to compounds having the general formula I ##STR1## where A if required can contain a functional and/or activated group C for coupling to selectively concentrating compounds or can contain a selectively concentrating compound coupled via the group C. B and B' are functional groups for coordinate bonding of groups carrying metal ions. The novel compounds are for forming complexes with radioactive metal ions, more particularly rhenium and technetium isotopes, and are used in medical diagnosis and therapy.