Method and systems for administering nitroglycerin transdermally at enhanced transdermal fluxes
US5302395A · kind A · utility
6Cited by
13References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 24, 1992 |
| Grant date | Apr 12, 1994 |
| Priority date | — |
| Expiry date | Jul 24, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Transdermal delivery systems for delivery of nitroglycerin are disclosed which deliver the drug at enhanced transdermal fluxes. The systems include, in addition to nitroglycerin, a permeation enhancer which is either a sorbitan ester, a C.sub.8 -C.sub.22 aliphatic alcohol, or a mixture thereof. Methods for administering nitroglycerin using such permeation enhancers are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.