Chemotactic test apparatus and method
US5302515A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Aug 20, 1992 |
| Grant date | Apr 12, 1994 |
| Priority date | — |
| Expiry date | Aug 20, 2012 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/0406
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention is a single site or multiple site chemotaxis test apparatus or chemotaxis chamber for measuring the effect of concentration gradients of diffusible chemicals upon the directional response of biological cells. The chemotactic test apparatus of the present invention comprise two compartments separated by a thin passage. The dimensions of the thin passage are selected such that cells cannot flow through the thin passage, but must deform themselves by flattening out and then "crawl" or migrate through the passage. These chambers can be used to study the migration or orientation of mobile adherent or non-adherent cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.