Process for the enzymatic separation of the optical isomers of alpha-substituted carboxylic acids using esterase from Brevibacterium imperiale
US5302528A · kind A · utility
5Cited by
4References
6Claims
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Key dates
| Filing date | Apr 22, 1992 |
| Grant date | Apr 12, 1994 |
| Priority date | — |
| Expiry date | Apr 22, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/84
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A process is described for the separation of the optical isomers of alphayl- or alpha-aryloxy- carboxylic acids by means of the stereoselective hydrolysis of racemic alkyl esters of the above acids in the presence of bacteria or their enzymes, selected from the species Brevibacterium, Bacteridium, Micrococcus, and Bacillus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.