Patent · US Expired

27-hydroxyrapamycin and derivatives thereof

US5302600A · kind A · utility

3Cited by
21References
3Claims
0Family size

Assignee

Inventor

Key dates

Filing dateJul 22, 1993
Grant dateApr 12, 1994
Priority date
Expiry dateJul 22, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D498/18
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

This invention provides a compound of formula I, ##STR1## and 27-substituted derivatives thereof which are useful as immunosuppressive, anti-inflammatory, antifungal, antitumor, and antiproliferative agents. The compound depicted by formula I is named 27-hydroxyrapamycin, and may also be referred to as 27-deoxo-27-hydroxyrapamycin.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.