6-O-methylerythromycin A oxime derivatives
US5302705A · kind A · utility
4Cited by
5References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 1, 1990 |
| Grant date | Apr 12, 1994 |
| Priority date | — |
| Expiry date | Oct 1, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A 6-O-methylerythromycin A oxime derivative represented by the formula ##STR1## wherein X is a substituted benzyl group, a substituted phenyl group, an .alpha.-methylbenzyl group, an .alpha.-methylphenethyl group, a diphenylmethyl group, a trityl group, a dibenzosuberanyl group, or a group of the formula --(CH.sub.2).sub.n --R, and Y is a hydrogen atom, a substituted phenyl group or a 2-aminothiazol-4-ylmethylcarbonyl group, and a pharmaceutically acceptable salt thereof are disclosed. These compounds have antibacterial activity against erythromycin resistant bacteria.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.