Patent · US Expired

2-substituted quinolines, and their use in medicaments

US5304563A · kind A · utility

4Cited by

3References

15Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Siegfried Raddatz · Hanerau-Hademarschen, DE
Klaus-Helmut Mohrs · Wuppertal, DE
Michael Matzke · Wuppertal, DE
Romanis Fruchtmann · Cologne, DE
Armin Hatzelmann · Konstanz, DE
Christian Kohlsdorfer · Lechenich, DE
Reiner Muller-Peddinghaus · Bensberg, DE
Pia Theisen-Popp · Bensberg, DE

Key dates

Filing date	Oct 28, 1992
Grant date	Apr 19, 1994
Priority date	—
Expiry date	Oct 28, 2012

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D215/14
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The title compounds are prepared either by reacting the corresponding halogenomethylquinolines with substituted phenols, optionally subsequently alkylating these or hydrolysing esters to acids, or by reacting phenyl-substituted quinolinecarboxylic acid derivatives with sulphonamides. The new phenyl-substituted quinolines are utilizable as active substances in medicaments, in particular as lipoxygenase inhibitors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.