Apparatus for delivering nitroglycerin to the skin, processes for the production thereof and the use thereof

US5306502A · kind A · utility

Assignee

• LTS Lohmann Therapie-Systeme GmbH Co. KG · DE

Inventors

• Halvor Jaeger · Neu-Ulm, DE
• Hans-Rainer Hoffmann · Neuwied, DE
• Reinhold Meconi · Neuwied, DE
• Robert-Peter Klein · Neuwied, DE

Key dates

• Filing date: Mar 30, 1992
• Grant date: Apr 26, 1994
• Expiry date: Mar 30, 2012

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/521
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to an apparatus for the controlled delivery or release of nitroglycerin to the human or animal skin, preferably in plaster form with a nitroglycerin-impermeable backing layer, a one or multiple-part reservoir containing a pressure sensitive adhesive nitroglycerin in uniform or irregular distribution and optionally a removable protective layer impermeable for nitroglycerin, the reservoir being produced using hot melt pressure sensitive adhesives with a processing temperature of 40.degree. to 80.degree. C., preferably 40.degree. to 60.degree. C. and in particularly preferred manner 40.degree. to 45.degree. C., a process for the production thereof and the use of the apparatus for therapeutic purposes in human and veterinary medicine.