DNA encoding immunogenic gpIII glycoprotein of varicella-zoster virus
US5306635A · kind A · utility
1Cited by
2References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 9, 1992 |
| Grant date | Apr 26, 1994 |
| Priority date | — |
| Expiry date | Jun 9, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/16722
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A gene of varicella-zoster virus (VZV) which encodes immunogenic outer surface viral proteins has been identified by DNA sequence analysis. Antibodies directed against peptides imputed from the DNA sequence can react with the glycoprotein, which itself is reactive with neutralizing antibodies. The amino-terminal sequence of the purified glycoprotein is identical to a portion of the amino acid sequence imputed from the DNA sequence. This glycoprotein is useful for the preparation of a vaccine against VZV.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.