Certain aryl a cycloalkyl fused imidazopyrazinols; and new class of GABA brain receptor ligands
US5306819A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 27, 1992 |
| Grant date | Apr 26, 1994 |
| Priority date | — |
| Expiry date | Aug 27, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention encompasses structures of the formula: ##STR1## and the pharmaceutically acceptable non-toxic salts thereof wherein: ##STR2## where W represents an aromatic group substituted with various organic and inorganic substituents; PA1 X, Y are hydrogen, halogen, hydroxy or amino with the proviso that at least X or Y is hydroxy; PA1 A, B C, and D, represent nitrogen or a carbon atom substituted with various organic and inorganic substituents; PA1 E represents oxygen, sulfur or substituted nitrogen; PA1 R.sub.3, R.sub.4, R.sub.12, and R.sub.13 are variables representing various organic and inorganic substituents; and PA1 n is 0, 1, or 2.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.