Physostigmine derivatives with acetylcholinesterase inhibition properties, and the relative production process

US5306825A · kind A · utility

Assignee

• CONSIGLIO NAZIONALE DELLE RICERCHE · IT

Inventors

• Mario Brufani · Roma, IT
• Claudio Castelland · Roma, IT
• Maurizio Marta · Roma, IT
• Alberto Oliverio · Roma, IT
• Flaminia Pavone · Roma, IT
• Massimo Pomponi · Roma, IT

Key dates

• Filing date: Apr 26, 1989
• Grant date: Apr 26, 1994
• Expiry date: Apr 26, 2009

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Physostigmine derivatives with acetylcholinesterase inhibition properties, of general formula: ##STR1## in which R is a linear alkyl of from 2 to 20 C. atoms, a branched alkyl, a cycloalkyl or an aryl, when R' is H, or R and R' are linear alkyl of from 2 to 20 C. atoms.