High molecular mass N,O-sulphated heparosans, process for their preparation and the pharmaceutical compositions which contain them
US5314876A · kind A · utility
19Cited by
1References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 30, 1992 |
| Grant date | May 24, 1994 |
| Priority date | — |
| Expiry date | Nov 30, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P7/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The subject of the invention is new high molecular mass N,O-sulphated heparosans consisting of chains or of a mixture of chains having a molecular mass of between 1.5.times.10.sup.4 and 4.0.times.10.sup.6 D, characterised by a repeating disaccharide structure of formula I: ##STR1## in which E represents, in 0 to 80% of the disaccharide units of the said N,O-sulphated heparosan, an acetyl group and, in the remaining disaccharide units, a sulphate group and optionally a hydrogen atom, G represents a hydrogen atom and a sulphate group, and the pharmaceutically acceptable salts of the said N,O-sulphated heparosans.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.