Process for the single crystallization of enatiomeric ratio's (2S,3S):(2R,3R) of substituted 1,5-benzothiazepinone
US5315005A · kind A · utility
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3Claims
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Key dates
| Filing date | Jan 25, 1993 |
| Grant date | May 24, 1994 |
| Priority date | — |
| Expiry date | Jan 25, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D281/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A purification method of intermediates for the preparation of Diltiazem which consists of the crystallization of a mixture enantiomerically enriched in (2S,3S)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H) -one is described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.