Microorganism for breaking down moenomycins, a process for the breakdown, and the use of the breakdown products

US5315038A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Werner Aretz · Königstein, DE
• Dirk Bottger · Liederbach, DE
• Gerhard Seibert · Darmstadt, DE
• Alois Tumulka · Königstein, DE
• Peter Welzel · Bochum, DE
• Kurt Hobert · Bochum, DE

Key dates

• Filing date: Apr 20, 1993
• Grant date: May 24, 1994
• Expiry date: Apr 20, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12R2001/07
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A new microorganism for breaking down moenomycins, a process for the breakdown, and the use of the breakdown products are disclosed. A new Bacillus species and the appropriate enzymes obtained therefrom can be used to break down phosphoglycolipid antibiotics. The breakdown products of moenomycins display antibiotic activity or can be used as building blocks for the synthetic preparation of transglycosylase inhibitors.