Patent · US Expired

T-cell receptor specific for antigen polypeptides and related polynucleotides

US5316925A · kind A · utility

9Cited by
6References
47Claims
0Family size

Inventors

Key dates

Filing dateDec 3, 1992
Grant dateMay 31, 1994
Priority date—
Expiry dateDec 3, 2012

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Oligonucleotide sequences are provided coding for T-cell-specific antigen receptors or fragments thereof. The oligonucleotide sequences can be used as probes for detecting helper and cytotoxic T-cells, preparing and isolating DNA sequences encoding for the receptor polypeptide, and in constructions for expression of receptor polypeptides or fragments thereof. In addition, processing signals from the receptor subunits can be employed in conjunction with modified wild type oligonucleotide sequences or non-wild type oligonucleotide sequences. TM86 was deposited at the A.T.C.C. on Mar. 1, 1984 and given Accession No. 40099. TT11 was deposited at the A.T.C.C. on Oct. 22, 1984 and given Accession No. 40141.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.