Azacyclic bisphosphonates as anticholesterolemic agents
US5317015A · kind A · utility
5Cited by
3References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 1, 1992 |
| Grant date | May 31, 1994 |
| Priority date | — |
| Expiry date | May 1, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/66
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to a method of lowering abnormally high serum cholesterol levels in the body without significantly reducing mevalonic metabolite synthesis and to novel pharmacological compositions containing as an active ingredient bisphosphonic acid and ester compounds containing a mono-, bi- or tricyclic ring linked with a bisphosphonate moiety through a basic amino alkylene group. This invention also provides novel bisphosphonate compounds and the processes for their preparation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.